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George S Bailey Selected Research

chlorophyllin (copper chlorophyll)

11/2009E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.
2/2009Identifying efficacious approaches to chemoprevention with chlorophyllin, purified chlorophylls and freeze-dried spinach in a mouse model of transplacental carcinogenesis.
3/2007The importance of carcinogen dose in chemoprevention studies: quantitative interrelationships between, dibenzo[a,l]pyrene dose, chlorophyllin dose, target organ DNA adduct biomarkers and final tumor outcome.
10/2006Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.
2/2006Post-initiation chlorophyllin exposure does not modulate aflatoxin-induced foci in the liver and colon of rats.
12/2004The dietary phytochemical chlorophyllin alters E-cadherin and beta-catenin expression in human colon cancer cells.
2/2003Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.

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George S Bailey Research Topics

Disease

19Neoplasms (Cancer)
08/2012 - 02/2002
11Carcinogenesis
08/2012 - 02/2003
5Colonic Neoplasms (Colon Cancer)
08/2012 - 12/2004
2Neoplasm Metastasis (Metastasis)
07/2007 - 12/2004
2Aberrant Crypt Foci
01/2007 - 02/2003
1Cardiovascular Diseases (Cardiovascular Disease)
08/2012
1Chronic Disease (Chronic Diseases)
08/2012
1Nervous System Diseases (Neurological Disorders)
08/2012
1Lymphoma (Lymphomas)
01/2006
1Leukemia
01/2006
1Body Weight (Weight, Body)
01/2006
1Adenoma (Adenomas)
01/2006
1Acute-Phase Reaction
12/2005
1Hepatocellular Carcinoma (Hepatoma)
12/2005
1Breast Neoplasms (Breast Cancer)
02/2002

Drug/Important Bio-Agent (IBA)

11CarcinogensIBA
08/2012 - 01/2003
8ChlorophyllIBA
02/2012 - 02/2003
7chlorophyllin (copper chlorophyll)IBA
11/2009 - 02/2003
6dibenzo(a,l)pyreneIBA
02/2012 - 01/2006
5beta CateninIBA
04/2008 - 02/2003
5PhytochemicalsIBA
07/2007 - 02/2003
4Biomarkers (Surrogate Marker)IBA
02/2012 - 03/2007
4indole-3-carbinolIBA
10/2006 - 02/2002
32- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA
08/2012 - 01/2007
3DNA AdductsIBA
02/2012 - 03/2007
3DNA (Deoxyribonucleic Acid)IBA
11/2009 - 03/2007
3Messenger RNA (mRNA)IBA
04/2008 - 01/2006
2AminesIBA
08/2012 - 01/2007
2benzocycloheptapyridineIBA
08/2012 - 01/2007
2TeaIBA
04/2008 - 01/2007
2Proteins (Proteins, Gene)FDA Link
04/2008 - 10/2006
2Aflatoxin B1 (Aflatoxin B)IBA
03/2008 - 12/2005
2AflatoxinsIBA
06/2007 - 12/2005
2Dimenhydrinate (DMH)FDA LinkGeneric
10/2006 - 02/2003
2Amino AcidsFDA Link
10/2006 - 02/2003
21,2-Dimethylhydrazine (1,2 Dimethylhydrazine)IBA
10/2006 - 02/2003
2Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA
10/2006 - 01/2006
1MicroRNAs (MicroRNA)IBA
08/2012
1Carrier Proteins (Binding Protein)IBA
08/2012
1Bromodeoxyuridine (BrdU)IBA
11/2009
1Therapeutic UsesIBA
11/2009
1Ribonucleotide Reductases (Ribonucleotide Reductase)IBA
11/2009
1CoffeeFDA Link
04/2008
1Caffeine (No Doz)FDA LinkGeneric
04/2008
1TomatineIBA
12/2007
1IndolesIBA
07/2007
13,3'-diindolylmethane (diindolylmethane)IBA
07/2007
1chlorinIBA
03/2007
1EnzymesIBA
01/2007
1Cyclin D1IBA
10/2006
1Codon (Codons)IBA
01/2006
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
01/2006
1Fumigant 93 (D-D)IBA
01/2006
1AntioxidantsIBA
01/2006
1Ascorbic Acid (Vitamin C)FDA LinkGeneric
01/2006
1Vitamin EFDA LinkGeneric
01/2006
1Carotenoids (Carotene)IBA
01/2006
1Plant ExtractsIBA
01/2006
1Pharmaceutical PreparationsIBA
12/2005
1Vitamin A (Retinol)FDA LinkGeneric
12/2005
1OligonucleotidesIBA
12/2005
1Cadherins (E-Cadherin)IBA
12/2004
1Differentiation AntigensIBA
12/2004
1CopperIBA
02/2003
1Proto-Oncogene Proteins c-junIBA
02/2003
1Glycogen Synthase (Synthase I)IBA
02/2003
1quinolineIBA
02/2003
1Drinking WaterIBA
02/2003

Therapy/Procedure

4Chemoprevention
02/2012 - 03/2007
1Drug Therapy (Chemotherapy)
12/2004
1Lasers (Laser)
12/2004